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Hepatocarcinogenesis Prevention by Pirfenidone Is PPARγ Mediated and Involves Modification of Nuclear NF-kB p65/p50 Ratio

Targeted therapies for regulating processes such as inflammation, apoptosis, and fibrogenesis might modulate human HCC development. Pirfenidone (PFD) has shown anti-fibrotic and anti-inflammatory functions in both clinical and experimental studies. The aim of this study was to evaluate PPARγ express...

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Detalles Bibliográficos
Autores principales:	Silva-Gomez, Jorge Antonio, Galicia-Moreno, Marina, Sandoval-Rodriguez, Ana, Miranda-Roblero, Hipolito Otoniel, Lucano-Landeros, Silvia, Santos, Arturo, Monroy-Ramirez, Hugo Christian, Armendariz-Borunda, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583060/ https://www.ncbi.nlm.nih.gov/pubmed/34768791 http://dx.doi.org/10.3390/ijms222111360

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