Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase

SIMPLE SUMMARY: Cyclin-dependent kinases (CDKs) are rich and viable therapeutic targets for various cancers. The emergence of event-driven pharmacology as an alternative to occupancy-driven pharmacology has begun to address the challenges associated with selectively targeting CDKs. In this review ar...

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Detalles Bibliográficos
Autores principales: Rana, Sandeep, Mallareddy, Jayapal Reddy, Singh, Sarbjit, Boghean, Lidia, Natarajan, Amarnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583118/
https://www.ncbi.nlm.nih.gov/pubmed/34771669
http://dx.doi.org/10.3390/cancers13215506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583118/
https://www.ncbi.nlm.nih.gov/pubmed/34771669
http://dx.doi.org/10.3390/cancers13215506

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