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Dual Hyaluronic Acid and Folic Acid Targeting pH-Sensitive Multifunctional 2DG@DCA@MgO-Nano-Core–Shell-Radiosensitizer for Breast Cancer Therapy
SIMPLE SUMMARY: In this study, we have developed CD44 and folate receptor-targeting multi-functional dual drug-loaded nanoparticles. This comprises hyaluronic acid (HA) and folic acid (FA) conjugated to 2-deoxy glucose (2DG) and a shell linked to a dichloroacetate (DCA) and magnesium oxide (MgO) cor...
Autores principales: | Askar, Mostafa A., Thabet, Noura M., El-Sayyad, Gharieb S., El-Batal, Ahmed I., Abd Elkodous, Mohamed, El Shawi, Omama E., Helal, Hamed, Abdel-Rafei, Mohamed K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583154/ https://www.ncbi.nlm.nih.gov/pubmed/34771733 http://dx.doi.org/10.3390/cancers13215571 |
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