Cargando…
Neoantigen Dendritic Cell Vaccination Combined with Anti-CD38 and CpG Elicits Anti-Tumor Immunity against the Immune Checkpoint Therapy-Resistant Murine Lung Cancer Cell Line LLC1
SIMPLE SUMMARY: Despite the substantial achievements to date, a significant proportion of patients still fail to benefit from immune-checkpoint therapies (ICT). The absence of T cell infiltration and insufficient immune recognition may account for the primary resistance to immune checkpoint therapy....
Autores principales: | Sun, Changbo, Nagaoka, Koji, Kobayashi, Yukari, Nakagawa, Hidewaki, Kakimi, Kazuhiro, Nakajima, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583214/ https://www.ncbi.nlm.nih.gov/pubmed/34771674 http://dx.doi.org/10.3390/cancers13215508 |
Ejemplares similares
-
Identification of Neoantigens in Two Murine Gastric Cancer Cell Lines Leading to the Neoantigen-Based Immunotherapy
por: Nagaoka, Koji, et al.
Publicado: (2021) -
Deep immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy
por: Nagaoka, Koji, et al.
Publicado: (2020) -
CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells
por: Riehn, Mathias, et al.
Publicado: (2017) -
Immune subtypes and neoantigen-related immune evasion in advanced colorectal cancer
por: Sugawara, Toshitaka, et al.
Publicado: (2022) -
Nanostructured SL9-CpG Lipovaccines Elicit Immune Response for the Treatment of Melanoma
por: Mu, Li-Min, et al.
Publicado: (2019)