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Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection

Tumor involvement of major vascular structures limits surgical options in pancreatic adenocarcinoma (PDAC), which in turn limits opportunities for cure. Despite advances in locoregional approaches, there is currently no role for incomplete resection. This study evaluated a gelatinized neoantigen-tar...

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Detalles Bibliográficos
Autores principales: Delitto, Daniel, Zabransky, Daniel J., Chen, Fangluo, Thompson, Elizabeth D., Zimmerman, Jacquelyn W., Armstrong, Todd D., Leatherman, James M., Suri, Reecha, Lopez-Vidal, Tamara Y., Huff, Amanda L., Lyman, Melissa R., Guinn, Samantha R., Baretti, Marina, Kagohara, Luciane T., Ho, Won Jin, Azad, Nilofer S., Burns, William R., He, Jin, Wolfgang, Christopher L., Burkhart, Richard A., Zheng, Lei, Yarchoan, Mark, Zaidi, Neeha, Jaffee, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583296/
https://www.ncbi.nlm.nih.gov/pubmed/34777919
http://dx.doi.org/10.1080/2162402X.2021.2001159