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Structural Analysis and Spatiotemporal Expression of Atxn1 Genes in Zebrafish Embryos and Larvae

Zebrafish have come into focus to model cerebellar diseases such as spinocerebellar ataxias (SCAs), which is caused by an expansion of translated CAG repeats in several unrelated genes. In spinocerebellar ataxia type 1 (SCA1), gain-of-function in the mutant ATXN1 contributes to SCA1’s neuropathy. Hu...

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Detalles Bibliográficos
Autores principales:	Vauti, Franz, Vögele, Viktoria, Deppe, Isabel, Hahnenstein, Susanne T., Köster, Reinhard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583371/ https://www.ncbi.nlm.nih.gov/pubmed/34768779 http://dx.doi.org/10.3390/ijms222111348

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