Human Islet Amyloid Polypeptide Overexpression in INS-1E Cells Influences Amylin Oligomerization under ER Stress and Oxidative Stress

Human amylin or islet amyloid polypeptide (hIAPP) is synthesized in the pancreatic β-cells and has been shown to contribute to the pathogenesis of type 2 diabetes (T2D) in vitro and in vivo. This study compared amylin oligomerization/expression and signal transduction under endoplasmic reticulum (ER...

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Detalles Bibliográficos
Autores principales: Yoo, Yeong-Min, Joo, Seong Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583535/
https://www.ncbi.nlm.nih.gov/pubmed/34768769
http://dx.doi.org/10.3390/ijms222111341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583535/
https://www.ncbi.nlm.nih.gov/pubmed/34768769
http://dx.doi.org/10.3390/ijms222111341

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