Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin Microscopy

SIMPLE SUMMARY: Little is known about how cancer cells adapt their mechanical properties in complex 3D microenvironments. Here we generated different types of tumor spheroids within compliant or stiff hydrogels. We then quantitatively mapped the mechanical properties of these spheroids in situ using...

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Detalles Bibliográficos
Autores principales: Mahajan, Vaibhav, Beck, Timon, Gregorczyk, Paulina, Ruland, André, Alberti, Simon, Guck, Jochen, Werner, Carsten, Schlüßler, Raimund, Taubenberger, Anna Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583550/
https://www.ncbi.nlm.nih.gov/pubmed/34771711
http://dx.doi.org/10.3390/cancers13215549

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