A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism

CYP102A1 (BM3) is a catalytically self-sufficient flavocytochrome fusion protein isolated from Bacillus megaterium, which displays similar metabolic capabilities to many drug-metabolizing human P450 isoforms. BM3′s high catalytic efficiency, ease of production and malleable active site makes the enz...

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Detalles Bibliográficos
Autores principales: Thistlethwaite, Sian, Jeffreys, Laura N., Girvan, Hazel M., McLean, Kirsty J., Munro, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583553/
https://www.ncbi.nlm.nih.gov/pubmed/34768811
http://dx.doi.org/10.3390/ijms222111380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583553/
https://www.ncbi.nlm.nih.gov/pubmed/34768811
http://dx.doi.org/10.3390/ijms222111380

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