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Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities

Oral ingestion is the predominant pathway of metal(loid)s exposure. In this study, the health risks of typical metal(loid)s (including Mn, As, Cr, Cd, and Pb) via multi-source, oral pathways for children aged 3–12 years, living in an area of China dominated by the electronic manufacturing industry,...

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Autores principales: Wang, Beibei, Lin, Chunye, Cheng, Hongguang, Duan, Xiaoli, Wang, Qin, Xu, Dongqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583640/
https://www.ncbi.nlm.nih.gov/pubmed/34769926
http://dx.doi.org/10.3390/ijerph182111409
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author Wang, Beibei
Lin, Chunye
Cheng, Hongguang
Duan, Xiaoli
Wang, Qin
Xu, Dongqun
author_facet Wang, Beibei
Lin, Chunye
Cheng, Hongguang
Duan, Xiaoli
Wang, Qin
Xu, Dongqun
author_sort Wang, Beibei
collection PubMed
description Oral ingestion is the predominant pathway of metal(loid)s exposure. In this study, the health risks of typical metal(loid)s (including Mn, As, Cr, Cd, and Pb) via multi-source, oral pathways for children aged 3–12 years, living in an area of China dominated by the electronic manufacturing industry, were studied based on the field sampling of duplicated diet, soil, and drinking water. Child-specific ingestion parameters were measured (except the soil ingestion rates, which were from a previous study of the same population), and a Monte Carlo method was applied to determine the uncertainty of the risk assessment. It was observed that children living in such environments were at risk of metal(loid)s exposure, with the accumulative carcinogenic risk exceeding the maximum acceptable level. Food intake was identified to be the primary exposure pathway. Moreover, Pb and Cr were the major risk elements to local children’s health. Compared with primary school students, kindergarten children experienced a higher risk. This study highlights that high attention should be paid to children living in suburban areas dominated by the electronic manufacturing industry, and that priority should be given to studies on metal(loid)s exposure deriving from different types of food and their corresponding bioavailability, in order to further discern the precise risk sources to protect children’s health.
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spelling pubmed-85836402021-11-12 Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities Wang, Beibei Lin, Chunye Cheng, Hongguang Duan, Xiaoli Wang, Qin Xu, Dongqun Int J Environ Res Public Health Article Oral ingestion is the predominant pathway of metal(loid)s exposure. In this study, the health risks of typical metal(loid)s (including Mn, As, Cr, Cd, and Pb) via multi-source, oral pathways for children aged 3–12 years, living in an area of China dominated by the electronic manufacturing industry, were studied based on the field sampling of duplicated diet, soil, and drinking water. Child-specific ingestion parameters were measured (except the soil ingestion rates, which were from a previous study of the same population), and a Monte Carlo method was applied to determine the uncertainty of the risk assessment. It was observed that children living in such environments were at risk of metal(loid)s exposure, with the accumulative carcinogenic risk exceeding the maximum acceptable level. Food intake was identified to be the primary exposure pathway. Moreover, Pb and Cr were the major risk elements to local children’s health. Compared with primary school students, kindergarten children experienced a higher risk. This study highlights that high attention should be paid to children living in suburban areas dominated by the electronic manufacturing industry, and that priority should be given to studies on metal(loid)s exposure deriving from different types of food and their corresponding bioavailability, in order to further discern the precise risk sources to protect children’s health. MDPI 2021-10-29 /pmc/articles/PMC8583640/ /pubmed/34769926 http://dx.doi.org/10.3390/ijerph182111409 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Beibei
Lin, Chunye
Cheng, Hongguang
Duan, Xiaoli
Wang, Qin
Xu, Dongqun
Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title_full Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title_fullStr Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title_full_unstemmed Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title_short Health Risk Assessment of Metals via Multi-Source Oral Exposure for Children Living in Areas with Intense Electronic Manufacturing Activities
title_sort health risk assessment of metals via multi-source oral exposure for children living in areas with intense electronic manufacturing activities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583640/
https://www.ncbi.nlm.nih.gov/pubmed/34769926
http://dx.doi.org/10.3390/ijerph182111409
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