Aberrant Upregulation of Indoleamine 2,3-Dioxygenase 1 Promotes Proliferation and Metastasis of Hepatocellular Carcinoma Cells via Coordinated Activation of AhR and β-Catenin Signaling

Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide. Chronic liver inflammation due to hepatitis virus infection and other major effectors is a major risk factor of HCC. Indoleamine 2,3-dioxygenase 1 (IDO1), a heme enzyme highly expressed upon stimulation...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Ta, Wu, Pei-Hua, Hu, Chia-Chi, Nien, Hsiao-Ching, Wang, Jin-Town, Sheu, Jin-Chuan, Chow, Lu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583706/
https://www.ncbi.nlm.nih.gov/pubmed/34769098
http://dx.doi.org/10.3390/ijms222111661

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