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BDNF-Overexpressing Engineered Mesenchymal Stem Cells Enhances Their Therapeutic Efficacy against Severe Neonatal Hypoxic Ischemic Brain Injury

We investigated whether irradiated brain-derived neurotropic factor (BDNF)-overexpressing engineered human mesenchymal stem cells (BDNF-eMSCs) improve paracrine efficiency and, thus, the beneficial potency of naïve MSCs against severe hypoxic ischemic (HI) brain injury in newborn rats. Irradiated BD...

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Detalles Bibliográficos
Autores principales:	Ahn, So Yoon, Sung, Dong Kyung, Chang, Yun Sil, Sung, Se In, Kim, Young Eun, Kim, Hyo-Jin, Lee, Soon Min, Park, Won Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583727/ https://www.ncbi.nlm.nih.gov/pubmed/34768827 http://dx.doi.org/10.3390/ijms222111395

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