Cargando…
The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target
Malignant mesothelioma (MM) is a highly aggressive cancer with limited therapeutic options. We have previously shown that the endocytic collagen receptor, uPARAP, is upregulated in certain cancers and can be therapeutically targeted. Public RNA expression data display uPARAP overexpression in MM. Th...
Autores principales: | Çakılkaya, Pınar, Sørensen, Rikke Raagaard, Jürgensen, Henrik Jessen, Krigslund, Oliver, Gårdsvoll, Henrik, Nielsen, Christoffer F., Santoni-Rugiu, Eric, Behrendt, Niels, Engelholm, Lars H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583732/ https://www.ncbi.nlm.nih.gov/pubmed/34768883 http://dx.doi.org/10.3390/ijms222111452 |
Ejemplares similares
-
The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)
por: MELANDER, MARIA C., et al.
Publicado: (2015) -
Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins
por: Jürgensen, Henrik J., et al.
Publicado: (2019) -
The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers
por: Nielsen, Christoffer Fagernæs, et al.
Publicado: (2017) -
Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis
por: Madsen, Daniel H., et al.
Publicado: (2013) -
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion
por: Engelholm, Lars H., et al.
Publicado: (2003)