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IL-15 Prevents Renal Fibrosis by Inhibiting Collagen Synthesis: A New Pathway in Chronic Kidney Disease?

Chronic kidney disease (CKD), secondary to renal fibrogenesis, is a public health burden. The activation of interstitial myofibroblasts and excessive production of extracellular matrix (ECM) proteins are major events leading to end-stage kidney disease. Recently, interleukin-15 (IL-15) has been impl...

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Detalles Bibliográficos
Autores principales: Devocelle, Aurore, Lecru, Lola, Ferlicot, Sophie, Bessede, Thomas, Candelier, Jean-Jacques, Giron-Michel, Julien, François, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583733/
https://www.ncbi.nlm.nih.gov/pubmed/34769128
http://dx.doi.org/10.3390/ijms222111698