Cargando…

Therapeutic Targeting of Alternative RNA Splicing in Gastrointestinal Malignancies and Other Cancers

Recent comprehensive genomic studies including single-cell RNA sequencing and characterization have revealed multiple processes by which protein-coding and noncoding RNA processing are dysregulated in many cancers. More specifically, the abnormal regulation of mRNA and precursor mRNA (pre-mRNA) proc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sahin, Ilyas, George, Andrew, Seyhan, Attila A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583749/ https://www.ncbi.nlm.nih.gov/pubmed/34769221 http://dx.doi.org/10.3390/ijms222111790

Ejemplares similares

Therapeutic Applications of Targeted Alternative Splicing to Cancer Treatment
por: Lin, Jung-Chun
Publicado: (2017)

Therapeutic Targeting of RNA Splicing in Cancer
por: Bonner, Elizabeth A., et al.
Publicado: (2023)

Alternative Splicing in Myeloid Malignancies
por: Gurnari, Carmelo, et al.
Publicado: (2021)

MicroRNA and Alternative mRNA Splicing Events in Cancer Drug Response/Resistance: Potent Therapeutic Targets
por: Marima, Rahaba, et al.
Publicado: (2021)

Regulation of RNA Splicing: Aberrant Splicing Regulation and Therapeutic Targets in Cancer
por: Kitamura, Koji, et al.
Publicado: (2021)

The Role of Alternative RNA Splicing in the Regulation of hTERT, Telomerase, and Telomeres: Implications for Cancer Therapeutics
por: Slusher, Aaron L., et al.
Publicado: (2020)

Alternative RNA splicing: contribution to pain and potential therapeutic strategy
por: Donaldson, Lucy F., et al.
Publicado: (2016)

Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities
por: Manabile, Mosebo Armstrong, et al.
Publicado: (2023)

Therapeutic Targeting Strategies of Cancer Stem Cells in Gastrointestinal Malignancies
por: Sonbol, Mohamad B., et al.
Publicado: (2019)

Alternative Splicing: Expanding the Landscape of Cancer Biomarkers and Therapeutics
por: Bessa, Cláudia, et al.
Publicado: (2020)

Impacts and mechanisms of alternative mRNA splicing in cancer metabolism, immune response, and therapeutics
por: Peng, Qiu, et al.
Publicado: (2022)

Alternative Splicing as a Target for Cancer Treatment
por: Martinez-Montiel, Nancy, et al.
Publicado: (2018)

Alternative Splicing in the Hippo Pathway—Implications for Disease and Potential Therapeutic Targets
por: Porazinski, Sean, et al.
Publicado: (2018)

Alternative Splicing: A New Therapeutic Target for Ovarian Cancer
por: Yao, Shijie, et al.
Publicado: (2022)

Alternative Splicing in Breast Cancer and the Potential Development of Therapeutic Tools
por: Martínez-Montiel, Nancy, et al.
Publicado: (2017)

Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer
por: Li, Junyi, et al.
Publicado: (2021)

Alternative mRNA Splicing and Promising Therapies in Cancer
por: Fackenthal, James D.
Publicado: (2023)

Therapeutic Targeting of Alternative Splicing: A New Frontier in Cancer Treatment
por: Murphy, Anthony J., et al.
Publicado: (2022)

Alternative splicing of BCL-X and implications for treating hematological malignancies
por: Chen, Wanling, et al.
Publicado: (2021)

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia()
por: Hulse, R.P., et al.
Publicado: (2014)

Alternative splicing in endothelial cells: novel therapeutic opportunities in cancer angiogenesis
por: Di Matteo, Anna, et al.
Publicado: (2020)

Alternative RNA Splicing—The Trojan Horse of Cancer Cells in Chemotherapy
por: Mehterov, Nikolay, et al.
Publicado: (2021)

Mechanisms of non-coding RNA-modulated alternative splicing in cancer
por: Wang, Xiaolin, et al.
Publicado: (2022)

The role of alternative pre-mRNA splicing in cancer progression
por: Choi, Sunkyung, et al.
Publicado: (2023)

Histone Marks-Dependent Effect on Alternative Splicing: New Perspectives for Targeted Splicing Modulation in Cancer?
por: Imbriano, Carol, et al.
Publicado: (2022)

Alternative mRNA Splicing in the Pathogenesis of Obesity
por: Wong, Chi-Ming, et al.
Publicado: (2018)

Targeting alternative splicing in cancer immunotherapy
por: Han, Nan, et al.
Publicado: (2023)

Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer
por: Zhang, Shengliang, et al.
Publicado: (2022)

Therapeutic targeting of alternative splicing to inhibit hepatocellular carcinoma metastasis
por: Lee, Yun-Han
Publicado: (2022)

miRNA-Based Regulation of Alternative RNA Splicing in Metazoans
por: Schorr, Anna L., et al.
Publicado: (2021)

Regulation of Flowering Time and Other Developmental Plasticities by 3’ Splicing Factor-Mediated Alternative Splicing in Arabidopsis thaliana
por: Lee, Keh Chien, et al.
Publicado: (2023)

Aberrant RNA splicing and therapeutic opportunities in cancers
por: Yamauchi, Hirofumi, et al.
Publicado: (2021)

Alternative RNA splicing in tumour heterogeneity, plasticity and therapy
por: Öther-Gee Pohl, Sebastian, et al.
Publicado: (2022)

Role of RNA Alternative Splicing in T Cell Function and Disease
por: Banerjee, Shefali, et al.
Publicado: (2023)

Aberrant alternative splicing in breast cancer
por: Yang, Quan, et al.
Publicado: (2019)

Alternative Splicing in Cancer and Immune Cells
por: Bernard, Antoine, et al.
Publicado: (2022)

Regulation of Epithelial-Mesenchymal Transitions by Alternative Splicing: Potential New Area for Cancer Therapeutics
por: Li, Ling, et al.
Publicado: (2023)

Splicing and alternative splicing in rice and humans
por: E, Zhiguo, et al.
Publicado: (2013)

Targeted therapy in gastrointestinal malignancies
por: Chhatrala, Ravi, et al.
Publicado: (2014)

Alternative splicing in cardiomyopathy
por: Beqqali, A.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_uh7k0tmnopl79rqcq4efqde9fi