Cargando…

Vitamin B Mitigates Thoracic Aortic Dilation in Marfan Syndrome Mice by Restoring the Canonical TGF-β Pathway

Thoracic aortic aneurysm (TAA) formation is a multifactorial process that results in diverse clinical manifestations and drug responses. Identifying the critical factors and their functions in Marfan syndrome (MFS) pathogenesis is important for exploring personalized medicine for MFS. Methylenetetra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Tzu-Heng, Chang, Hsiao-Huang, Guo, Yu-Ru, Chang, Wei-Chiao, Chen, Yi-Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583889/ https://www.ncbi.nlm.nih.gov/pubmed/34769168 http://dx.doi.org/10.3390/ijms222111737

Ejemplares similares

Divergent effects of canonical and non‐canonical TGF‐β signalling on mixed contractile‐synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms
por: Pedroza, Albert J., et al.
Publicado: (2019)

New Screening Tool for Aortic Root Dilation in Children with Marfan Syndrome and Marfan-Like Disorders
por: Wozniak-Mielczarek, Lidia, et al.
Publicado: (2020)

Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome
por: Asano, Keiichi, et al.
Publicado: (2022)

Does altered aortic flow in marfan syndrome relate to aortic root dilatation?
por: Wang, Hung‐Hsuan, et al.
Publicado: (2016)

Epigenetic control of vascular smooth muscle cells in Marfan and non-Marfan thoracic aortic aneurysms
por: Gomez, Delphine, et al.
Publicado: (2011)

The revised role of TGF-β in aortic aneurysms in Marfan syndrome
por: Franken, R., et al.
Publicado: (2014)

TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome
por: You, Wei, et al.
Publicado: (2019)

Aortic root dilation in adult patients with Marfan syndrome: Does aortic root stiffness matter?
por: Cox, Kelly, et al.
Publicado: (2022)

Association of TGF-β Canonical Signaling-Related Core Genes With Aortic Aneurysms and Aortic Dissections
por: Chen, Jicheng, et al.
Publicado: (2022)

Androgens Accentuate TGF‐β Dependent Erk/Smad Activation During Thoracic Aortic Aneurysm Formation in Marfan Syndrome Male Mice
por: Tashima, Yasushi, et al.
Publicado: (2020)

No Beneficial Effect of General and Specific Anti-Inflammatory Therapies on Aortic Dilatation in Marfan Mice
por: Franken, Romy, et al.
Publicado: (2014)

Angiotensin, transforming growth factor β and aortic dilatation in Marfan syndrome: Of mice and humans()
por: Yu, Christopher, et al.
Publicado: (2018)

Characterization of doxycycline-mediated inhibition of Marfan syndrome-associated aortic dilation by multiphoton microscopy
por: Tehrani, Arash Y., et al.
Publicado: (2020)

Marfan's cardiomyopathy is associated with aortic annular and root dilatation in the absence of significant valvular regurgitation
por: Wong, Joyce, et al.
Publicado: (2009)

17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice
por: Saddic, Louis, et al.
Publicado: (2023)

17 β-Estradiol Impedes Aortic Root Dilation and Rupture in Male Marfan Mice
por: Saddic, Louis, et al.
Publicado: (2023)

Thoracic Aortic Aneurysm Surgery in Marfan Patients: a Perspective from the UK
por: Harky, Amer, et al.
Publicado: (2020)

A novel variant in fibrillin-1 is responsible for early-onset familial thoracic aortic aneurysms in Marfan patients
por: Duan, Yanyu, et al.
Publicado: (2021)

Progressive Pulmonary Artery Dilatation is Associated with Type B Aortic Dissection in Patients with Marfan Syndrome
por: Brouwer, Christel, et al.
Publicado: (2019)

Magnetic resonance angiography derived predictors of progressive dilatation and surgery of the aortic root in Marfan syndrome
por: Weinrich, Julius Matthias, et al.
Publicado: (2022)

Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease
por: Grewal, Nimrat, et al.
Publicado: (2023)

Outcomes of thoracic aortic interventions in Marfan syndrome in the state of Texas over 11 years
por: Mikulski, Matthew F, et al.
Publicado: (2023)

Application of Whole Exome Sequencing and Functional Annotations to Identify Genetic Variants Associated with Marfan Syndrome
por: Lin, Min-Rou, et al.
Publicado: (2022)

Resveratrol Inhibits Aortic Root Dilatation in the Fbn1(C1039G/+) Marfan Mouse Model
por: Hibender, Stijntje, et al.
Publicado: (2016)

Losartan for Preventing Aortic Root Dilatation in Patients with Marfan Syndrome: A Meta-Analysis of Randomized Trials
por: Elbadawi, Ayman, et al.
Publicado: (2019)

Beta-Blocker Use during Pregnancy Correlates with Less Aortic Root Dilatation in Patients with Marfan's Syndrome
por: Roberts, Emma A., et al.
Publicado: (2023)

Obstructive Sleep Apnea, Palatal Morphology, and Aortic Dilatation in Marfan Syndrome Growing Subjects: A Retrospective Study
por: Laganà, Giuseppina, et al.
Publicado: (2021)

Treatment With Methotrexate Associated With Lipid Core Nanoparticles Prevents Aortic Dilation in a Murine Model of Marfan Syndrome
por: Guido, Maria Carolina, et al.
Publicado: (2022)

Snoring and aortic dimension in Marfan syndrome
por: Sowho, Mudiaga, et al.
Publicado: (2022)

Thoracic Aortic Dilation: Implications for Physical Activity and Sport Participation
por: Monda, Emanuele, et al.
Publicado: (2022)

Anesthetic management of a patient with Marfan syndrome and severe aortic root dilatation undergoing cholecystectomy and partial hepatic resection
por: Ghatak, Tanmoy, et al.
Publicado: (2013)

Can 10 000 Healthy Steps a Day Slow Aortic Root Dilation in Pediatric Patients With Marfan Syndrome?
por: Selamet Tierney, Elif Seda, et al.
Publicado: (2022)

Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling
por: Dawson, Ashley, et al.
Publicado: (2021)

Treatment experience of thoracic aortic aneurysm recurrence after multiple surgeries for Marfan syndrome: A case report
por: Chen, Huai-Dong, et al.
Publicado: (2019)

Male–female differences in quality of life and coping style in patients with Marfan syndrome and hereditary thoracic aortic diseases
por: Thijssen, Carlijn G. E., et al.
Publicado: (2020)

Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol
por: Mieremet, Arnout, et al.
Publicado: (2022)

Dilatation of the Great Arteries in an Infant with Marfan Syndrome and Ventricular Septal Defect
por: Rozendaal, L., et al.
Publicado: (2011)

Acute Aortic Dissection in Pregnancy with the Marfan Syndrome
por: Kim, Si Wook, et al.
Publicado: (2014)

Prophilactic aortic-root reconstruction in Marfan syndrome
por: Szabolcs, Z, et al.
Publicado: (2013)

Sex, pregnancy and aortic disease in Marfan syndrome
por: Renard, Marjolijn, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4ffcvkl0or11b6o5h96sasa8h2