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Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice

Space is a high-stress environment. One major risk factor for the astronauts when they leave the Earth’s magnetic field is exposure to ionizing radiation from galactic cosmic rays (GCR). Several adverse changes occur in mammalian anatomy and physiology in space, including bone loss. In this study, w...

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Detalles Bibliográficos
Autores principales: Kim, Ha-Neui, Richardson, Kimberly K., Krager, Kimberly J., Ling, Wen, Simmons, Pilar, Allen, Antino R., Aykin-Burns, Nukhet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583929/
https://www.ncbi.nlm.nih.gov/pubmed/34769141
http://dx.doi.org/10.3390/ijms222111711