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Direct and Indirect Effect of TGFβ on Treg Transendothelial Recruitment in HCC Tissue Microenvironment
The balance between anti-tumor and tumor-promoting immune cells, such as CD4+ Th1 and regulatory T cells (Tregs), respectively, is assumed to dictate the progression of hepatocellular carcinoma (HCC). The transforming growth factor beta (TGFβ) markedly shapes the HCC microenvironment, regulating the...
Autores principales: | Dituri, Francesco, Mancarella, Serena, Serino, Grazia, Chaoul, Nada, Lupo, Luigi Giovanni, Villa, Erica, Fabregat, Isabel, Giannelli, Gianluigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583957/ https://www.ncbi.nlm.nih.gov/pubmed/34769191 http://dx.doi.org/10.3390/ijms222111765 |
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