Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in Mice

Involvement of the Toll-like receptor 4 (TLR4) in maladaptive cardiac remodeling and heart failure (HF) upon pressure overload has been studied extensively, but less is known about the role of TLR2. Interplay and redundancy of TLR4 with TLR2 have been reported in other organs but were not investigat...

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Detalles Bibliográficos
Autores principales: Kessler, Elise L., Wang, Jiong-Wei, Kok, Bart, Brans, Maike A., Nederlof, Angelique, van Stuijvenberg, Leonie, Huang, Chenyuan, Vink, Aryan, Arslan, Fatih, Efimov, Igor R., Lam, Carolyn S. P., Vos, Marc A., de Kleijn, Dominique P. V., Fontes, Magda S. C., van Veen, Toon A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583975/
https://www.ncbi.nlm.nih.gov/pubmed/34769252
http://dx.doi.org/10.3390/ijms222111823

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