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Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration

miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We prese...

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Detalles Bibliográficos
Autores principales: Archacka, Karolina, Ciemerych, Maria A., Florkowska, Anita, Romanczuk, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583994/
https://www.ncbi.nlm.nih.gov/pubmed/34768999
http://dx.doi.org/10.3390/ijms222111568
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author Archacka, Karolina
Ciemerych, Maria A.
Florkowska, Anita
Romanczuk, Karolina
author_facet Archacka, Karolina
Ciemerych, Maria A.
Florkowska, Anita
Romanczuk, Karolina
author_sort Archacka, Karolina
collection PubMed
description miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.
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spelling pubmed-85839942021-11-12 Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration Archacka, Karolina Ciemerych, Maria A. Florkowska, Anita Romanczuk, Karolina Int J Mol Sci Review miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being. MDPI 2021-10-26 /pmc/articles/PMC8583994/ /pubmed/34768999 http://dx.doi.org/10.3390/ijms222111568 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Archacka, Karolina
Ciemerych, Maria A.
Florkowska, Anita
Romanczuk, Karolina
Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_full Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_fullStr Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_full_unstemmed Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_short Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
title_sort non-coding rnas as regulators of myogenesis and postexercise muscle regeneration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583994/
https://www.ncbi.nlm.nih.gov/pubmed/34768999
http://dx.doi.org/10.3390/ijms222111568
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