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Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We prese...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583994/ https://www.ncbi.nlm.nih.gov/pubmed/34768999 http://dx.doi.org/10.3390/ijms222111568 |
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author | Archacka, Karolina Ciemerych, Maria A. Florkowska, Anita Romanczuk, Karolina |
author_facet | Archacka, Karolina Ciemerych, Maria A. Florkowska, Anita Romanczuk, Karolina |
author_sort | Archacka, Karolina |
collection | PubMed |
description | miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being. |
format | Online Article Text |
id | pubmed-8583994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85839942021-11-12 Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration Archacka, Karolina Ciemerych, Maria A. Florkowska, Anita Romanczuk, Karolina Int J Mol Sci Review miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being. MDPI 2021-10-26 /pmc/articles/PMC8583994/ /pubmed/34768999 http://dx.doi.org/10.3390/ijms222111568 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Archacka, Karolina Ciemerych, Maria A. Florkowska, Anita Romanczuk, Karolina Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title | Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title_full | Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title_fullStr | Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title_full_unstemmed | Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title_short | Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration |
title_sort | non-coding rnas as regulators of myogenesis and postexercise muscle regeneration |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8583994/ https://www.ncbi.nlm.nih.gov/pubmed/34768999 http://dx.doi.org/10.3390/ijms222111568 |
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