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Methotrexate Alters the Expression of microRNA in Fibroblast-like Synovial Cells in Rheumatoid Arthritis

We aimed to investigate the effect of methotrexate (MTX) on microRNA modulation in rheumatoid arthritis fibroblast-like synovial cells (RA-FLS). RA-FLS were treated with MTX for 48 h. We then performed miRNA array analysis to investigate differentially expressed miRNAs. Transfection with miR-877-3p...

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Detalles Bibliográficos
Autores principales: Iwamoto, Naoki, Furukawa, Kaori, Endo, Yushiro, Shimizu, Toshimasa, Sumiyoshi, Remi, Umeda, Masataka, Koga, Tomohiro, Kawashiri, Shin-ya, Igawa, Takashi, Ichinose, Kunihiro, Tamai, Mami, Origuchi, Tomoki, Kawakami, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584010/
https://www.ncbi.nlm.nih.gov/pubmed/34768991
http://dx.doi.org/10.3390/ijms222111561

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