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Retinal Degeneration and Microglial Dynamics in Mature Progranulin-Deficient Mice
Progranulin (PGRN) is a secreted glycoprotein that regulates numerous cellular processes. The role of PGRN as a regulator of lysosomes has recently received attention. The purpose of this study was to characterize the retinal phenotype in mature PGRN knockout (Grn(−/−)) mice. The a-wave amplitude of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584076/ https://www.ncbi.nlm.nih.gov/pubmed/34768987 http://dx.doi.org/10.3390/ijms222111557 |