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Retinal Degeneration and Microglial Dynamics in Mature Progranulin-Deficient Mice

Progranulin (PGRN) is a secreted glycoprotein that regulates numerous cellular processes. The role of PGRN as a regulator of lysosomes has recently received attention. The purpose of this study was to characterize the retinal phenotype in mature PGRN knockout (Grn(−/−)) mice. The a-wave amplitude of...

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Detalles Bibliográficos
Autores principales:	Takahashi, Kei, Nakamura, Shinsuke, Shimazawa, Masamitsu, Hara, Hideaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584076/ https://www.ncbi.nlm.nih.gov/pubmed/34768987 http://dx.doi.org/10.3390/ijms222111557

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