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Classification and Functional Analysis between Cancer and Normal Tissues Using Explainable Pathway Deep Learning through RNA-Sequencing Gene Expression

Deep learning has proven advantageous in solving cancer diagnostic or classification problems. However, it cannot explain the rationale behind human decisions. Biological pathway databases provide well-studied relationships between genes and their pathways. As pathways comprise knowledge frameworks...

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Detalles Bibliográficos
Autores principales: Park, Sangick, Huang, Eunchong, Ahn, Taejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584109/
https://www.ncbi.nlm.nih.gov/pubmed/34768960
http://dx.doi.org/10.3390/ijms222111531