Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response

Parkinson’s disease (PD) is a prevalent movement disorder characterized by the progressive loss of dopaminergic neurons in substantia nigra pars compacta (SNpc). The 6-hydroxydopamine (6-OHDA) lesion is still one of the most widely used techniques for modeling Parkinson’s disease (PD) in rodents. De...

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Detalles Bibliográficos
Autores principales: Mendes-Pinheiro, Bárbara, Soares-Cunha, Carina, Marote, Ana, Loureiro-Campos, Eduardo, Campos, Jonas, Barata-Antunes, Sandra, Monteiro-Fernandes, Daniela, Santos, Diogo, Duarte-Silva, Sara, Pinto, Luísa, José Salgado, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584172/
https://www.ncbi.nlm.nih.gov/pubmed/34768962
http://dx.doi.org/10.3390/ijms222111530

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