Insulin and α-Tocopherol Enhance the Protective Effect of Each Other on Brain Cortical Neurons under Oxidative Stress Conditions and in Rat Two-Vessel Forebrain Ischemia/Reperfusion Injury

Clinical trials show that insulin administered intranasally is a promising drug to treat neurodegenerative diseases, but at high doses its use may result in cerebral insulin resistance. Identifying compounds which could enhance the protective effects of insulin, may be helpful to reduce its effectiv...

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Detalles Bibliográficos
Autores principales: Zakharova, Irina O., Bayunova, Liubov V., Zorina, Inna I., Sokolova, Tatiana V., Shpakov, Alexander O., Avrova, Natalia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584186/
https://www.ncbi.nlm.nih.gov/pubmed/34769198
http://dx.doi.org/10.3390/ijms222111768

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