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5-Aminolevulinic Acid Attenuates Glucose-Regulated Protein 78 Expression and Hepatocyte Lipoapoptosis via Heme Oxygenase-1 Induction

Endoplasmic reticulum (ER) stress plays a pivotal role in the progression of steatohepatitis. 5-aminolevulinic acid (5-ALA), a precursor in the heme biosynthetic pathway, has recently been reported to induce heme oxygenase (HO)-1. HO-1 exerts important cytoprotective actions. In this study, we aimed...

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Detalles Bibliográficos
Autores principales: Hashimoto, Takaaki, Sugihara, Takaaki, Kanda, Tsutomu, Takata, Tomoaki, Isomoto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584191/
https://www.ncbi.nlm.nih.gov/pubmed/34768836
http://dx.doi.org/10.3390/ijms222111405