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Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl(4) Exposure in Mice

Myeloid cells play an essential role in the maintenance of liver homeostasis, as well as the initiation and termination of innate and adaptive immune responses. In chronic hepatic inflammation, the production of transforming growth factor beta (TGF-β) is pivotal for scarring and fibrosis induction a...

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Detalles Bibliográficos
Autores principales: Unrau, Ludmilla, Endig, Jessica, Goltz, Diane, Sprezyna, Paulina, Ulrich, Hanna, Hagenstein, Julia, Geers, Bernd, Kaftan, Karina, Heukamp, Lukas Carl, Tiegs, Gisa, Diehl, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584252/
https://www.ncbi.nlm.nih.gov/pubmed/34769006
http://dx.doi.org/10.3390/ijms222111575