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Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl(4) Exposure in Mice
Myeloid cells play an essential role in the maintenance of liver homeostasis, as well as the initiation and termination of innate and adaptive immune responses. In chronic hepatic inflammation, the production of transforming growth factor beta (TGF-β) is pivotal for scarring and fibrosis induction a...
Autores principales: | Unrau, Ludmilla, Endig, Jessica, Goltz, Diane, Sprezyna, Paulina, Ulrich, Hanna, Hagenstein, Julia, Geers, Bernd, Kaftan, Karina, Heukamp, Lukas Carl, Tiegs, Gisa, Diehl, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584252/ https://www.ncbi.nlm.nih.gov/pubmed/34769006 http://dx.doi.org/10.3390/ijms222111575 |
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