PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway

Background: Oral squamous cell carcinoma (OSCC) has a high prevalence and predicted global mortality rate of 67.1%, necessitating better therapeutic strategies. Moreover, the recurrence and resistance of OSCC after chemo/radioresistance remains a major bottleneck for its effective treatment. Molecul...

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Detalles Bibliográficos
Autores principales: Pai, Shin, Yadav, Vijesh Kumar, Kuo, Kuang-Tai, Pikatan, Narpati Wesa, Lin, Chun-Shu, Chien, Ming-Hsien, Lee, Wei-Hwa, Hsiao, Michael, Chiu, Shao-Chih, Yeh, Chi-Tai, Tsai, Jo-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584253/
https://www.ncbi.nlm.nih.gov/pubmed/34768921
http://dx.doi.org/10.3390/ijms222111492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584253/
https://www.ncbi.nlm.nih.gov/pubmed/34768921
http://dx.doi.org/10.3390/ijms222111492

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