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Probing the Structural Dynamics of the Activation Gate of KcsA Using Homo-FRET Measurements

The allosteric coupling between activation and inactivation processes is a common feature observed in K(+) channels. Particularly, in the prokaryotic KcsA channel the K(+) conduction process is controlled by the inner gate, which is activated by acidic pH, and by the selectivity filter (SF) or outer...

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Detalles Bibliográficos
Autores principales: Díaz-García, Clara, Renart, Maria Lourdes, Poveda, José Antonio, Giudici, Ana Marcela, González-Ros, José M., Prieto, Manuel, Coutinho, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584343/
https://www.ncbi.nlm.nih.gov/pubmed/34769384
http://dx.doi.org/10.3390/ijms222111954