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CD38 Correlates with an Immunosuppressive Treg Phenotype in Lupus-Prone Mice

CD38 is a transmembrane glycoprotein expressed by T-cells. It has been reported that patients with systemic lupus erythematosus (SLE) showed increased CD38(+)CD25(+) T-cells correlating with immune activation and clinical signs. Contrariwise, CD38 deficiency in murine models has shown enhanced autoi...

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Detalles Bibliográficos
Autores principales: Pérez-Lara, Jocelyn C., Espinosa, Enrique, Santos-Argumedo, Leopoldo, Romero-Ramírez, Héctor, López-Herrera, Gabriela, García-García, Fabio, Sandoval-Montes, Claudia, Ortiz-Navarrete, Vianney, Flores-Muñoz, Mónica, Rodríguez-Alba, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584421/
https://www.ncbi.nlm.nih.gov/pubmed/34769406
http://dx.doi.org/10.3390/ijms222111977