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An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate

An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the...

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Autores principales: Barac, Sorin, Onofrei, Roxana Ramona, Neagoe, Petru Vlad, Popescu, Alexandra Ioana, Pantea, Stelian, Rață, Andreea Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584433/
https://www.ncbi.nlm.nih.gov/pubmed/34768611
http://dx.doi.org/10.3390/jcm10215083
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author Barac, Sorin
Onofrei, Roxana Ramona
Neagoe, Petru Vlad
Popescu, Alexandra Ioana
Pantea, Stelian
Rață, Andreea Luciana
author_facet Barac, Sorin
Onofrei, Roxana Ramona
Neagoe, Petru Vlad
Popescu, Alexandra Ioana
Pantea, Stelian
Rață, Andreea Luciana
author_sort Barac, Sorin
collection PubMed
description An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the risk of amputation in these patients after revascularization procedures. The secondary goal was to find the correlation between acute limb ischemia (ALI) severity, patient comorbidities, risk of death, and the association of SARS-CoV-2 infection. The patients were treated by open surgery (18 patients—81.81%) or by the means of endovascular techniques (four patients—18.18%). The amputation-free survival rate was 81.81% in hospital and 86.36% at 1-month follow-up. In this study, the presence of SARS-CoV-2 infection did not influence the amputation-free survival rate: it was only the risk factor for the arterial thrombosis and the trigger for the acute ischemic event. The application of the standard treatment—open surgery or endovascular revascularization—in patients with acute limb ischemia and SARS-CoV-2 infection represents the key to success for lower limb salvage.
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spelling pubmed-85844332021-11-12 An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate Barac, Sorin Onofrei, Roxana Ramona Neagoe, Petru Vlad Popescu, Alexandra Ioana Pantea, Stelian Rață, Andreea Luciana J Clin Med Article An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the risk of amputation in these patients after revascularization procedures. The secondary goal was to find the correlation between acute limb ischemia (ALI) severity, patient comorbidities, risk of death, and the association of SARS-CoV-2 infection. The patients were treated by open surgery (18 patients—81.81%) or by the means of endovascular techniques (four patients—18.18%). The amputation-free survival rate was 81.81% in hospital and 86.36% at 1-month follow-up. In this study, the presence of SARS-CoV-2 infection did not influence the amputation-free survival rate: it was only the risk factor for the arterial thrombosis and the trigger for the acute ischemic event. The application of the standard treatment—open surgery or endovascular revascularization—in patients with acute limb ischemia and SARS-CoV-2 infection represents the key to success for lower limb salvage. MDPI 2021-10-29 /pmc/articles/PMC8584433/ /pubmed/34768611 http://dx.doi.org/10.3390/jcm10215083 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barac, Sorin
Onofrei, Roxana Ramona
Neagoe, Petru Vlad
Popescu, Alexandra Ioana
Pantea, Stelian
Rață, Andreea Luciana
An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_full An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_fullStr An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_full_unstemmed An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_short An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_sort observational study on patients with acute limb ischemia and sars-cov-2 infection: early and late results in limb salvage rate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584433/
https://www.ncbi.nlm.nih.gov/pubmed/34768611
http://dx.doi.org/10.3390/jcm10215083
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