Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Promoted Osteogenesis by Increasing Vesicle Trafficking, Wnt/Ca(2+), and BMP/Smad Signaling

Sphingosine-1-phosphate receptor 2 (S1PR2) is a G protein-coupled receptor that regulates various immune responses. Herein, we determine the effects of a S1PR2 antagonist (JTE013) or a S1PR2 shRNA on osteogenesis by culturing murine bone marrow stromal cells (BMSCs) in osteogenic media with JTE013,...

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Detalles Bibliográficos
Autores principales: Lin, Simon, Pandruvada, Subramanya, Yu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584480/
https://www.ncbi.nlm.nih.gov/pubmed/34769490
http://dx.doi.org/10.3390/ijms222112060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584480/
https://www.ncbi.nlm.nih.gov/pubmed/34769490
http://dx.doi.org/10.3390/ijms222112060

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