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IRF3 Knockout Results in Partial or Complete Rejection of Murine Mesothelioma

Background: Malignant pleural mesothelioma (MESO) has a poor prognosis despite aggressive treatment with surgery, radiation and chemotherapy, and novel therapeutic approaches are needed. IRF3 is a downstream molecule of the cGAS/STING signaling pathway, but its roles have not been investigated in ME...

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Detalles Bibliográficos
Autores principales: Aoki, Masaya, Wu, Licun, Murakami, Junichi, Zhao, Yidan, Yun, Hana, de Perrot, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584553/
https://www.ncbi.nlm.nih.gov/pubmed/34768716
http://dx.doi.org/10.3390/jcm10215196

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