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Long-Term Safety and Efficacy of Subcutaneous Cladribine Used in Increased Dosage in Patients with Relapsing Multiple Sclerosis: 20-Year Observational Study
Cladribine is currently registered as a 10-milligram tablet formulation with a fixed cumulative dosage of 3.5 mg/kg over 2 years. It is important to investigate if an increased dosage may lead to further clinical stability with preserved safety. This study used an off-label subcutaneous (s.c.) formu...
Autores principales: | Rejdak, Konrad, Zasybska, Adriana, Pietruczuk, Aleksandra, Baranowski, Dariusz, Szklener, Sebastian, Kaczmarek, Magda, Stelmasiak, Zbigniew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584572/ https://www.ncbi.nlm.nih.gov/pubmed/34768726 http://dx.doi.org/10.3390/jcm10215207 |
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