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Functional Identification of Complement Factor D and Analysis of Its Expression during GCRV Infection in Grass Carp (Ctenopharyngodon idella)

Complement factor D (Df) is a serine protease well known for activating the alternative pathway (AP) in mammals by promoting the cleavage of complement component 3 (C3), thus becoming involved in innate defense. In teleost fish, however, the functional mechanisms of Df in the AP and against pathogen...

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Detalles Bibliográficos
Autores principales: Ding, Chunhua, Xiao, Tiaoyi, Qin, Beibei, Xu, Baohong, Lv, Zhao, Wang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584590/
https://www.ncbi.nlm.nih.gov/pubmed/34769442
http://dx.doi.org/10.3390/ijms222112011