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Synthesis and Characterization of Bis-Triazolyl-Pyridine Derivatives as Noncanonical DNA-Interacting Compounds

Besides the well-known double-helical conformation, DNA is capable of folding into various noncanonical arrangements, such as G-quadruplexes (G4s) and i-motifs (iMs), whose occurrence in gene promoters, replication origins, and telomeres highlights the breadth of biological processes that they might...

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Detalles Bibliográficos
Autores principales: Di Porzio, Anna, Galli, Ubaldina, Amato, Jussara, Zizza, Pasquale, Iachettini, Sara, Iaccarino, Nunzia, Marzano, Simona, Santoro, Federica, Brancaccio, Diego, Carotenuto, Alfonso, De Tito, Stefano, Biroccio, Annamaria, Pagano, Bruno, Tron, Gian Cesare, Randazzo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584640/
https://www.ncbi.nlm.nih.gov/pubmed/34769387
http://dx.doi.org/10.3390/ijms222111959