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AddaVax Formulated with PolyI:C as a Potential Adjuvant of MDCK-based Influenza Vaccine Enhances Local, Cellular, and Antibody Protective Immune Response in Mice

Poor immune responses to inactivated influenza vaccine can be improved by effective and safe adjuvants to increase antibody titers and cellular protective response. In our study, AddaVax and PolyI:C combined adjuvant (AP adjuvant) were used for influenza vaccine development. After immunizing BALB/c...

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Detalles Bibliográficos
Autores principales: Nian, Xuanxuan, Zhang, Jiayou, Deng, Tao, Liu, Jing, Gong, Zheng, Lv, Chuanshuo, Yao, Luyao, Li, Junying, Huang, Shihe, Yang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584644/
https://www.ncbi.nlm.nih.gov/pubmed/34766215
http://dx.doi.org/10.1208/s12249-021-02145-0

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