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Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance

Transforming growth factor-beta 1 (TGF-β1), a pro-fibrotic tumour-derived factor promotes fibroblast differentiation in the tumour microenvironment and is thought to contribute to the development of pro-tumourigenic cancer-associated fibroblasts (CAFs) by promoting myofibroblast differentiation. miR...

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Detalles Bibliográficos
Autores principales: Zainal Abidin, Siti Amalina Inche, Paterson, Ian Charles, Hunt, Stuart, Lambert, Daniel W., Higginbotham, Samuel, Pink, Ryan Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584782/
https://www.ncbi.nlm.nih.gov/pubmed/34762649
http://dx.doi.org/10.1371/journal.pone.0256812