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Microcirculatory Function during Endotoxemia—A Functional Citrulline-Arginine-NO Pathway and NOS3 Complex Is Essential to Maintain the Microcirculation

Competition for the amino acid arginine by endothelial nitric-oxide synthase (NOS3) and (pro-)inflammatory NO-synthase (NOS2) during endotoxemia appears essential in the derangement of the microcirculatory flow. This study investigated the role of NOS2 and NOS3 combined with/without citrulline suppl...

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Detalles Bibliográficos
Autores principales:	Wijnands, Karolina A. P., Meesters, Dennis M., Vandendriessche, Benjamin, Briedé, Jacob J., van Eijk, Hans M. H., Brouckaert, Peter, Cauwels, Anje, Lamers, Wouter H., Poeze, Martijn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584871/ https://www.ncbi.nlm.nih.gov/pubmed/34769369 http://dx.doi.org/10.3390/ijms222111940

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