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Modulation of Cellular NAD(+) Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of Neutrophil Extracellular Traps

Cancer-associated thrombosis is the second-leading cause of mortality in patients with cancer and presents a poor prognosis, with a lack of effective treatment strategies. NAD(P)H quinone oxidoreductase 1 (NQO1) increases the cellular nicotinamide adenine dinucleotide (NAD(+)) levels by accelerating...

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Detalles Bibliográficos
Autores principales: Cao, Wa, Zhu, Meng-Yu, Lee, Seung-Hoon, Lee, Su-Bin, Kim, Hyung-Jin, Park, Byung-Ouk, Yoon, Cheol-Hwan, Khadka, Dipendra, Oh, Gi-Su, Shim, Hyeok, Kwak, Tae-Hwan, So, Hong-Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584923/
https://www.ncbi.nlm.nih.gov/pubmed/34769515
http://dx.doi.org/10.3390/ijms222112085