High-Molecular-Weight Hyaluronic Acid Inhibits IL-1β-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-κB Signaling Pathway

Recent evidence has suggested that synovial inflammation and macrophage polarization were involved in the pathogenesis of osteoarthritis (OA). Additionally, high-molecular-weight hyaluronic acid (HMW-HA) was often used clinically to treat OA. GRP78, an endoplasmic reticulum (ER) stress chaperone, wa...

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Detalles Bibliográficos
Autores principales: Lee, Chien-Hsing, Chiang, Chi-Fu, Kuo, Feng-Chih, Su, Sheng-Chiang, Huang, Chia-Luen, Liu, Jhih-Syuan, Lu, Chieh-Hua, Hsieh, Chang-Hsun, Wang, Chih-Chien, Lee, Chian-Her, Shen, Pei-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584972/
https://www.ncbi.nlm.nih.gov/pubmed/34769349
http://dx.doi.org/10.3390/ijms222111917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584972/
https://www.ncbi.nlm.nih.gov/pubmed/34769349
http://dx.doi.org/10.3390/ijms222111917

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