Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells

Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to sialoglycans (sialic acid-containing glycans) on target cells. Despite the importance of Siglec-9 interactions in tumor immune evasion, their role a...

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Detalles Bibliográficos
Autores principales: Adeniji, Opeyemi S., Kuri-Cervantes, Leticia, Yu, Chenfei, Xu, Ziyang, Ho, Michelle, Chew, Glen M., Shikuma, Cecilia, Tomescu, Costin, George, Ashley F., Roan, Nadia R., Ndhlovu, Lishomwa C., Liu, Qin, Muthumani, Kar, Weiner, David B., Betts, Michael R., Xiao, Han, Abdel-Mohsen, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584986/
https://www.ncbi.nlm.nih.gov/pubmed/34762717
http://dx.doi.org/10.1371/journal.ppat.1010034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584986/
https://www.ncbi.nlm.nih.gov/pubmed/34762717
http://dx.doi.org/10.1371/journal.ppat.1010034

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