Low-Coverage Whole Genome Sequencing Using Laser Capture Microscopy with Combined Digital Droplet PCR: An Effective Tool to Study Copy Number and Kras Mutations in Early Lung Adenocarcinoma Development

Defining detailed genomic characterization of early tumor progression is critical to identifying key regulators and pathways in carcinogenesis as potentially druggable targets. In human lung cancer, work to characterize early cancer development has mainly focused on squamous cancer, as the earliest...

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Detalles Bibliográficos
Autores principales: Mickler, Elizabeth A., Zhou, Huaxin, Phang, Tzu L., Geraci, Mark W., Stearman, Robert S., Sears, Catherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584993/
https://www.ncbi.nlm.nih.gov/pubmed/34769463
http://dx.doi.org/10.3390/ijms222112034

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