Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans

To survive elevated temperatures, ectotherms adjust the fluidity of membranes by fine-tuning lipid desaturation levels in a process previously described to be cell autonomous. We have discovered that, in Caenorhabditis elegans, neuronal heat shock factor 1 (HSF-1), the conserved master regulator of...

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Detalles Bibliográficos
Autores principales: Chauve, Laetitia, Hodge, Francesca, Murdoch, Sharlene, Masoudzadeh, Fatemeh, Mann, Harry-Jack, Lopez-Clavijo, Andrea F., Okkenhaug, Hanneke, West, Greg, Sousa, Bebiana C., Segonds-Pichon, Anne, Li, Cheryl, Wingett, Steven W., Kienberger, Hermine, Kleigrewe, Karin, de Bono, Mario, Wakelam, Michael J. O., Casanueva, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585009/
https://www.ncbi.nlm.nih.gov/pubmed/34723964
http://dx.doi.org/10.1371/journal.pbio.3001431

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