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Functionally Heterogenous Macrophage Subsets in the Pathogenesis of Giant Cell Arteritis: Novel Targets for Disease Monitoring and Treatment

Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that affects adults above 50 years of age. In GCA, circulating monocytes are recruited to the inflamed arteries. With cues from the vascular microenvironment, they differentiate into macrophages and play important roles in the pat...

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Detalles Bibliográficos
Autores principales: Esen, Idil, Jiemy, William F., van Sleen, Yannick, van der Geest, Kornelis S.M., Sandovici, Maria, Heeringa, Peter, Boots, Annemieke M. H., Brouwer, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585092/
https://www.ncbi.nlm.nih.gov/pubmed/34768479
http://dx.doi.org/10.3390/jcm10214958

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