The Novel Positive Allosteric Modulator of the GABA(B) Receptor, KK-92A, Suppresses Alcohol Self-Administration and Cue-Induced Reinstatement of Alcohol Seeking in Rats

Positive allosteric modulators (PAMs) of the GABA(B) receptor (GABA(B) PAMs) are of interest in the addiction field due to their ability to suppress several behaviors motivated by drugs of abuse. KK-92A is a novel GABA(B) PAM found to attenuate intravenous self-administration of nicotine and reinsta...

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Detalles Bibliográficos
Autores principales: Maccioni, Paola, Kaczanowska, Katarzyna, Lawrence, Harshani, Yun, Sang, Bratzu, Jessica, Gessa, Gian Luigi, McDonald, Patricia, Colombo, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585307/
https://www.ncbi.nlm.nih.gov/pubmed/34778249
http://dx.doi.org/10.3389/fcell.2021.727576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585307/
https://www.ncbi.nlm.nih.gov/pubmed/34778249
http://dx.doi.org/10.3389/fcell.2021.727576

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