The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice

Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for maturation by the mitochondrial transporter ABCB7. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Lehrke, Michael Jonathan, Shapiro, Michael Jeremy, Rajcula, Matthew J, Kennedy, Madeleine M, McCue, Shaylene A, Medina, Kay L, Shapiro, Virginia Smith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585479/
https://www.ncbi.nlm.nih.gov/pubmed/34762046
http://dx.doi.org/10.7554/eLife.69621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585479/
https://www.ncbi.nlm.nih.gov/pubmed/34762046
http://dx.doi.org/10.7554/eLife.69621

Ejemplares similares