Cargando…

The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice

Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for maturation by the mitochondrial transporter ABCB7. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lehrke, Michael Jonathan, Shapiro, Michael Jeremy, Rajcula, Matthew J, Kennedy, Madeleine M, McCue, Shaylene A, Medina, Kay L, Shapiro, Virginia Smith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585479/ https://www.ncbi.nlm.nih.gov/pubmed/34762046 http://dx.doi.org/10.7554/eLife.69621

Ejemplares similares

Histone deacetylase 3 represses cholesterol efflux during CD4(+) T-cell activation
por: Wilfahrt, Drew, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

53BP1 is required for class switch recombination
por: Ward, Irene M., et al.
Publicado: (2004)

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4(+)CD8(+) thymocytes for CD4-lineage commitment
por: Philips, Rachael Laura, et al.
Publicado: (2019)

Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
por: Olson, Eli, et al.
Publicado: (2023)

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis
por: Harrington, Em P, et al.
Publicado: (2023)

Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
por: Milne, Kathryn, et al.
Publicado: (2021)

Cholesterol metabolism: a new molecular switch to control inflammation
por: Cardoso, Diana, et al.
Publicado: (2021)

Mechanistic diversity in MHC class I antigen recognition
por: Barbosa, Camila R. R., et al.
Publicado: (2021)

Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination
por: Hein, Katharina, et al.
Publicado: (1998)

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense
por: Krejčová, Gabriela, et al.
Publicado: (2019)

The meningeal transcriptional response to traumatic brain injury and aging
por: Bolte, Ashley C, et al.
Publicado: (2023)

NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors
por: Shapiro, Michael Jeremy, et al.
Publicado: (2019)

Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I
por: Leddy, Owen, et al.
Publicado: (2023)

TAPBPR mediates peptide dissociation from MHC class I using a leucine lever
por: Ilca, F Tudor, et al.
Publicado: (2018)

The recombinant anti-TNF-α fusion protein ameliorates rheumatoid arthritis by the protective role of autophagy
por: Chen, Xiaole, et al.
Publicado: (2020)

The μ Switch Region Tandem Repeats Are Important, but Not Required, for Antibody Class Switch Recombination
por: Luby, Thomas M., et al.
Publicado: (2001)

Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities
por: Russell, Magdalena L, et al.
Publicado: (2022)

Immunoglobulin class-switch recombination deficiencies
por: Durandy, Anne, et al.
Publicado: (2012)

AID function in somatic hypermutation and class switch recombination: AID function in somatic hypermutation and class switch recombination
por: Yu, Kefei
Publicado: (2022)

The role of G-density in switch region repeats for immunoglobulin class switch recombination
por: Zhang, Zheng Z., et al.
Publicado: (2014)

Increased susceptibility to dextran sulfate-induced mucositis of iron-overload β-thalassemia mice, another endogenous cause of septicemia in thalassemia
por: Visitchanakun, Peerapat, et al.
Publicado: (2021)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

Full thickness penile skin necrosis following HIPEC: Case report and literature review
por: Burg, Madeleine L., et al.
Publicado: (2020)

Quantitative Regulation of Class Switch Recombination by Switch Region Transcription
por: Lee, Chung-Gi, et al.
Publicado: (2001)

Tubular Adenoma in the Indiana Pouch of a Patient With a History of Bladder Exstrophy
por: Manka, Madeleine G., et al.
Publicado: (2015)

Epigenetic Codes Programing Class Switch Recombination
por: Vaidyanathan, Bharat, et al.
Publicado: (2015)

NME proteins regulate class switch recombination
por: Zheng, Simin, et al.
Publicado: (2018)

Making ends meet in class switch recombination
por: Wu, Lizhen, et al.
Publicado: (2020)

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity
por: Burbage, Marianne, et al.
Publicado: (2018)

Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination
por: He, Yafeng, et al.
Publicado: (2020)

Exploration of fine-scale recombination rate variation in the domestic horse
por: Beeson, Samantha K., et al.
Publicado: (2019)

Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain
por: Burns, Jeremy Carlos, et al.
Publicado: (2020)

Fixing DNA breaks during class switch recombination
por: Jolly, Christopher J., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_8eftv7g0h8o29eqkh2ppc0i2g6